Learning objectives
1. Knowledge and understanding. Students will have to acquire the pharmacokinetic and pharmacodynamic properties of the main drugs commonly used in developmental age. In particular, the concepts of general pharmacology, the clinical implications of pharmacokinetics, the characteristics of drug-receptor interaction, the main classes of receptors, the classes of drugs that modulate skeletal muscle contraction, antiepileptic drugs, drugs for pain treatment, chemotherapy antibiotics.
2. Ability to apply knowledge and understanding. Students will have to place the knowledge acquired in the physio-functional context of the human organism as a whole, to better understand the responses to the application of drugs of neuro- and psychomotor interest. This knowledge will be aimed at understanding the signs and/or symptoms that develop following the administration/taking of drugs and the evaluation of the effects they produce.
3. Independent judgment. The student will have to acquire the knowledge necessary in the future to plan study protocols for the characterization of new therapeutic protocols, once he enters the world of work as a graduate.
4. Communication skills. Students will have to acquire the terminological knowledge necessary to objectively describe the actions of drugs and to quantify their effects at the level of organs and systems in analytical terms, also for the purposes of a correct comparison between molecules with similar biological activities.
5. Learning ability. Students must be able to use what they have acquired to understand and interpret literature data relating to drugs, especially to finalize their use for research purposes in the clinical-pharmacological field.
Prerequisites
NO
Course unit content
The first part of the course concerns general pharmacology, both from the point of view of pharmacokinetics and pharmacodynamics. The second part specifically deals with some drugs active at the level of the CNS, of muscle contraction with both central and peripheral action and with analgesic properties.
Full programme
ENERAL PHARMACOLOGY
Principles of Pharmacokinetics (absorption, distribution, metabolism and elimination) and Pharmacodynamics (drug-receptor interaction and biological response, types of receptors).
SPECIAL PHARMACOLOGY
Classes of drugs that modulate skeletal muscle contraction with both central and peripheral action (benzodiazepines, baclofen, dantrolene, botulinum toxin, neuromuscular blockers...), antiepileptic drugs, drugs for the treatment of pain (NSAIDs), antibiotic chemotherapy.
Bibliography
Laurence L. Brunton
Goodman & Gilman
Le basi farmacologiche della terapia
Tredicesima edizione Zanichelli
Clark MA, Finkel JAR, Whalen, K. Le basi della farmacologia. Zanichelli seconda edizione.
F. Rossi, V. Cuomo, C. Riccardi. Farmacologia. Principi di base e applicazioni terapeutiche. Ed. Minerva Medica, IV edizione.
The lesson slides are available at the end of the course on the Elly platform.
Teaching methods
Frontal lessons with the support of slides.
The slides used to support the lessons, considered an integral part of the teaching material, will be uploaded on a weekly basis to the Elly platform.
Assessment methods and criteria
Written exam with multiple choice questions (N=10) and open questions (N=3).
Other information
RECEPTION TIME
Every day, by prior appointment by telephone or e-mail
email: mariapia.adorni@unipr.it
tel: 0521 903895
If necessary, the reception could take place remotely using the Teams platform
